Congratulations on making it to the final stage of Spore! You're now the
commander of your very own spaceship, which will allow you to explore
the far reaches of the galaxy! However, you'll first be tasked with a
few basic missions to help you get the hang of your ship. These include
scanning a creature, abducting it, dropping it off in your city, then
destroying the infected species (follow the radar waves that emit from
your ship and look for the yellow arrows marking the creatures). Once
finished, you'll be gifted an interplanetary drive which will allow you
to escape the confines of your planet's orbit and begin to explore the
galaxy. Continue to keep an eye on your goal box to stay informed of
your next objective.

Your Goal
The Space Stage is a bit more free-form than the others. That is,
while your ultimate goal is to expand your civilization across the
galaxy (by colonising other planets), there are countless missions you
can engage in during your journey, which provides quite a bit of
flexibility in how you go about this. Completing these missions will
earn you badges, which improves your rank and title, while unlocking new
tools and abilities that ultimately enhance your ability to expand your
civilization.
Combat
Early in your space career (and many times thereafter), you'll come
under attack from space aliens. Battling them is pretty basic: select a
weapon from your weapons menu and then blow them away. As you earn more
badges, be sure to purchase additional weaponry so you can stay
competitive. If you need to heal or refuel at any point, return to any
world in which you have founded a colony (including your home world) or
that of an ally for refreshment.
Tip: Because you will often have to
revisit your home planet, travelling back manually can quickly become
tedious. Thankfully, you can expedite the process by utilising the
"Return Ticket" item under your ship's "Main Tools" to make an instant
trip back home!
Terraforming & Colonising
As mentioned, your ultimate goal is to colonise as many planets as
you can. By doing so, you'll not only be able to extend your galactic
reach, but it also provides a steady income thanks to the spice
resources your colony mines (make sure to revisit your colonies
periodically to collect said spice). However, most planets are
uninhabitable until they have been terraformed—that is, you must make
the planet liveable by adjusting the temperature and atmosphere. 
When visiting a planet, a circular meter in the bottom-left corner
shows the current state of the atmosphere. Each ring within that circle
represents the different terraform levels, with the inner-ring
representing the best possible level, known as "T1." The icons bordering
the meter convey different information about the atmosphere—the ones to
the side represent temperature, while the icons above and below display
atmospheric pressure. The dot within that circular meter shows the
current level your atmosphere is at, and what you need to improve in
order to score better. For example, if the dot is in the top-right, that
indicates the planet is too hot and the atmosphere too dense to support
life. Ideally, you want that dot in the very centre to best support
life and your colonies.
Tip: Around each planet is an orbit
line; its colour dictates how easy the planet will be to terraform. Green
ones are easiest, while red and blue are more difficult.
In order to begin the terraforming process, you're going to need the
proper tools. Items such as the Cloud Seeder or Atmosphere Generator can
increase the atmosphere, whereas Ice Storm and Cloud Vacuum will lower
the temperature. As the dot on the atmosphere monitor moves inward to
better T-Levels, you're going to have to stabilise the atmosphere along
the way by planting various plants and creatures—if you don't do this
quickly, the atmosphere will destabilise, and essentially erase all of
your hard work.
To drop off plants and animals, access your cargo bay and lower them to
the planet using your tractor beam (if you need additional wildlife, you
can collect more from most other planets in the galaxy). Make sure to
populate the planet with plants of all three sizes (small, medium,
large) to further stabilise the atmosphere. Once you're done gardening,
it's time to add some creatures! Make sure to add herbivores first,
followed by the carnivores, otherwise the latter will become extinct due
to a lack of food.
Once you've stabilised the atmosphere, you may now plant a colony and add buildings as the T-Level improves!
Onward!
So that's the basics of Space Stage! Continue to explore the galaxy,
complete missions, and expand your empire to eventually dominate the
galaxy!
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